Tumor boards (team huddles) aren't enough to reach the goal.

eliminate abnormal growth in the pancreas because adiponectin has been reported to inhibit tumor cell growth and induce apoptosis (15). The finding by Bao et al. of an association between adiponec-tin and pancreatic cancer has both mechanistic and translational potential. Firmly establishing a link between adiponectin levels and pancreatic cancer risk will suggest that glucose/fat metabolism contributes to the pathophysiology of pancreatic cancer. Future studies in this direction are expected to help us better understand the molecular events that are responsible for pancreatic cancer tumorigenesis. Further studies on issues such as the dynamic changes of high/low-molecular-weight adiponectin levels during the development of pancreatic cancer can yield key information to determine whether plasma adiponectin levels could be used as a predictive biomarker. Currently, most cases of pancreatic cancer are diagnosed at a late stage, contributing to high mortality rates. Adiponectin assessment may be used to prescreen patients with metabolic disorders such as diabetes for the detection of pancreatic cancer at an early stage. Early detection by the assessment of adi-ponectin has the potential to improve the survival rates of pancre-atic tumor patients. It is also inviting to speculate that therapeutic interventions to increase the levels of circulating adiponectin may prevent the development of pancreatic cancer and/or improve the survival of patients with malignancy. mellitus and risk of pancreatic cancer: a meta-analysis of cohort studies. Sr, et al. Insulin resistance influences the association of adiponectin levels with diabetes incidence in two population-based cohorts: the Cooperative Health Research in the Region of Augsburg (KORA) S4/F4 study and the Framingham Offspring Study. A prospective study of circulating adipokine levels and risk of multiple myeloma. et al. The association of circulating adiponectin levels with pancreatic cancer risk: a study within the prospective EPIC cohort. Adiponectin as a potential differential marker to distinguish pancreatic cancer and chronic pancreatitis. SM, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. of adiponectin receptors that mediate antidiabetic metabolic effects. Ukkola O, et al. Low serum adiponectin level as a predictor of impaired glucose regulation and type 2 diabetes mellitus in a middle-aged Finnish population. isoforms in elderly patients with or without coronary artery disease. inhibits cell growth and induces apoptosis in human endometrial carci-noma cells, HEC-1-A and RL95 2. It is accepted for breast cancer that early detection and prompt treatment lead to better outcome. In this issue of the Journal, Vandergrift et al. (1) evaluate …